METRICH




Mechanism of action
Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.Folic acid is needed for the proper development of the human body. It is involved in producing the genetic material called DNA and in numerous other bodily functions.

Pyridoxine use for boosting the immune system, eye infections, bladder infections, and preventing cancer and kidney stones.Alpha-lipoic acid is used for diabetes and nerve-related symptoms of diabetes including burning, pain, and numbness in the legs and arms.

Indications
Treatment of fibromyalgia Syndrome 
Postherpetic neuralgia 
Anxiety 

Contraindications
Hypersensitivity, Pregnancy, lactation. Driving or working with machines, or do other dangerous activities. 

Adverse Drug Reactions
Oral: Anorexia, nausea, vomiting and diarrhoea. Parenteral: Rash, headache, hot sensation, diaphoresis 

Drug Interactions
Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives.

Storage 
Store at room temperature. Protect from moisture and light.





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